The School of Informatics, Computing, and Engineering Center for Bioinformatics Research Talk
Speaker: Bing Zhang, Baylor College of Medicine
Where: Indiana Memorial Union (IMU), Oak Room
When: Thursday, April 11, 2019, 3:00 pm
Topic: Proteogenomics: A New Avenue for Cancer Research
Abstract: Proteogenomics is a new research field at the interface of genomics and proteomics. In this talk, I will introduce our computational infrastructure and bioinformatics tools for cancer proteogenomic data analysis. Using proteogenomics data from the Clinical Proteomic Tumor Analysis Consortium (CPTAC), I will present a few examples on how proeogenomic integration can expand our knowledge on cancer genes, prioritize cancer drivers, clarify puzzling genomic observations, and correct misinterpreted gene functions. I will also discuss our recent works on using proteogenomics to identify tumor antigens and understand immune evasion mechanisms.
Biography: Dr. Zhang is Professor of Molecular and Human Genetics at the Baylor College of Medicine in Houston, Texas, USA. He is a CPRIT Scholar in Cancer Research, and a McNair Medical Institute Scholar. He received PhD degree in Genetics from the Chinese Academy of Sciences followed by a postdoctoral training in bioinformatics at the Oak Ridge National Laboratory. Before joining Baylor College of Medicine in August 2016, he had been a faculty member in the Department of Biomedical Informatics at the Vanderbilt University for ten years. Dr. Zhang’s research program focuses on integrating genomic and proteomic data to better understand cancer biology. He has more than 80 publications in the areas of bioinformatics, proteomics and cancer systems biology. He has served as principal investigator, bioinformatics director, or co-investigator on more than ten federal grants. He serves frequently as program committee member in international conferences and reviewer for NIH panels. He also serves on the editorial board of Molecular & Cellular Proteomics and Clinical Proteomics.